Production, absorption, distribution and excretion of vitamin B12 in sheep

Production, absorption, distribution and excretion of vitamin B 12 in sheep.

I. The efficiency of production and utilization of vitamin BIZ was studied with sheep given a cobalt-deficient diet with and without supplementary Co (I mg/d). Vitamin B,, to lignin ratios in rumen contents were used to estimate minimum rates of production and these were related to faecal and urinary excretion. Tissue distribution and excretion of vitamin Blz were studied with [58Co]cyanocobala...

Urinary excretion of vitamin B12.

rfHE ANNOUNCE\-IENT of the discoveryof vitamin 1312 in 1948 byRickes, et a!.’ in this coumitry amid hi y Smith, et al.2 in Emiglamid imiitiat-e(! its use in various climiical entities. The principal use has been in the treatment of permiicious -anemia. The dosage of this drug has beemi more or less empirically established!. The hematologic amid subjective responses of the patient with permiicio...

Carbachol and Vitamin B12 Absorption.

Absorption of vitamin B12 in rheumatoid arthritis.

Since auto-immunity may possibly be a common denominator in pernicious anaemia, thyroid dysfunction, and the rheumatic diseases, the suggested increased incidence ofpernicious anaemia in rheumatoid arthritis (Partridge and Duthie, 1963) is of considerable interest. Their figure of 1 4 per cent., which was five times higher than in their patients with other musculoskeletal disorders, was based o...

Absorption of vitamin B12 in tobacco amblyopia.

In view of the evidence that some abnormality of the metabolism of vitamin B12 is present in tobacco amblyopia (Callender and Denborough, I957; Heaton, McCormick, and Freeman, I958; Chisholm, Bronte-Stewart, and Foulds, I967), it was thought possible that absorption of the vitamin might be reduced in patients with the disease. The patients studied were male pipe smokers with bilateral acquired ...